Professional Practice: The Effects of Medication on Dysphagia in the Pediatric Population The effect of medications and drug interactions on pediatric dysphagia has generally not been discussed in the literature as frequently as other causative agents. Pediatric dysphagia, however, can be greatly affected by medications. “Oropharyngeal dysphagia due to iatrogenic neurological dysfunction may relate to either medication side effects or surgical ... Article
Article  |   June 01, 2001
Professional Practice: The Effects of Medication on Dysphagia in the Pediatric Population
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Professional Practice
Article   |   June 01, 2001
Professional Practice: The Effects of Medication on Dysphagia in the Pediatric Population
SIG 13 Perspectives on Swallowing and Swallowing Disorders (Dysphagia), June 2001, Vol. 10, 23-26. doi:10.1044/sasd10.2.23
SIG 13 Perspectives on Swallowing and Swallowing Disorders (Dysphagia), June 2001, Vol. 10, 23-26. doi:10.1044/sasd10.2.23
The effect of medications and drug interactions on pediatric dysphagia has generally not been discussed in the literature as frequently as other causative agents. Pediatric dysphagia, however, can be greatly affected by medications. “Oropharyngeal dysphagia due to iatrogenic neurological dysfunction may relate to either medication side effects or surgical complications. There are several general mechanisms by which neurological side effects of medications can cause or aggravate oropharyngeal dysphagia. These include decreased level of arousal, direct suppression of the brain stem swallowing regulation, movement disorders (dyskinesias, dystonias, and Parkinsonism), neuromuscular junction blockade, myopathy, oropharyngeal sensory impairment, and disturbance of salivation” (Buchholz, 1995, p. 248). For example, the anticonvulsant Phenytoin (Dilantin) has side effects of ataxia, dyskinesia, dysarthria, gingival hyperplasia, extrapyramidal syndrome and xerostomia (Deglin & Vallerand, 1999).
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